REJURAN: A SKIN REGENERATION BREAKTHROUGH THAT STARTED IN THE SEA
Rejuran might seem like the latest trend in anti-aging skincare, but behind the buzz lies a fascinating scientific origin story — one that begins not in a lab, but in the ocean.
This revolutionary skin treatment uses a highly purified molecule derived from salmon DNA to repair damaged skin, reduce inflammation, and promote collagen production. But how did scientists make the leap from marine biology to regenerative aesthetics?
Let’s dive into the history and research behind Rejuran, and why it’s become a go-to treatment.
WHERE DID REJURAN COME FROM?
Rejuran was first developed in South Korea, a country globally recognized for its leadership in cosmetic dermatology and regenerative medicine.
Scientists researching wound healing were particularly interested in polynucleotides (PN) — long-chain molecules that make up DNA. They found that when extracted and purified from salmon sperm cells, these PN molecules showed exceptional biocompatibility with human skin. In simple terms, the body recognizes the molecule as its own, and responds by healing and regenerating tissue.
The result? Improved skin structure, function, and appearance..
WHAT EXACTLY IS IN REJURAN?
The active ingredient in Rejuran is Polynucleotide (PN) or sometimes PDRN (Polydeoxyribonucleotide), depending on the formulation. These molecules:
- Stimulate fibroblasts, which are the skin cells responsible for collagen and elastin production
- Promote angiogenesis (the formation of new blood vessels), improving skin tone and hydration
- Enhance cell turnover and tissue repair
- Reduce inflammation and oxidative stress
Salmon DNA was chosen because it’s structurally very similar to human DNA, making it safe, stable, and effective when injected into the skin.
The Science: What Do Studies Say?
Clinical Study #1 – Journal of Cosmetic Dermatology (2016)
A study on the efficacy of PN injections over a 12-week period found:
- Improved dermal thickness
- Reduced fine lines and wrinkles
- Increased skin elasticity
Participants showed measurable improvement in skin texture and tone with minimal side effects.
Clinical Study #2 – Archives of Plastic Surgery (2019)
This study focused on PDRN (a form of PN used in Rejuran) and its regenerative effects:
- Demonstrated accelerated tissue repair
- Enhanced wound healing
- Decreased inflammation and scarring
The researchers concluded that PN-based treatments were clinically safe and effective for skin regeneration.
Additional Findings:
- Increased collagen synthesis within 2–3 weeks of treatment
- Normalization of damaged skin cells, especially useful for acne-scarred or aged skin
- Long-term improvement in skin barrier function
SO, WHAT DOES REJURAN ACTUALLY DO?
Think of Rejuran as a reset button for your skin. It doesn’t freeze muscles (like Botox), and it doesn’t add volume (like fillers). Instead, it works at a cellular level to:
- Stimulate collagen and elastin production
- Repair and restore skin barrier
- Improve texture, tone, and elasticity
- Fade acne scars and fine lines
- Soothe inflamed or damaged skin
It’s especially effective for:
- Fine lines around the eyes, mouth, and forehead
- Enlarged pores
- Acne scars
- Thinning or aging skin
- Dull, tired complexions
A NATURAL, EVIDENCE-BASED OPTION FOR SKIN REJUVENATION
Unlike many skin treatments that offer temporary surface-level changes, Rejuran delivers deep, long-lasting improvements by helping your body rebuild healthy skin from within.
Backed by clinical studies and real-world results, it’s a compelling option for those who want natural-looking results without going under the knife.
REGENERATION IS THE FUTURE OF SKINCARE
In the world of aesthetic medicine, regenerative treatments like Rejuran represent a new frontier. Rather than masking imperfections, they support the body’s own ability to heal, regenerate, and age beautifully.
Whether you’re battling post-acne scarring, early signs of aging, or simply want your healthiest skin yet, Rejuran offers a safe, proven path to long-term skin health.
Want to experience it for yourself?
San Jose locals can book a Rejuran consultation now at B.TOX.BAR.
Let your skin do what it was designed to do: heal itself — with a little help from science.
